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Phloretin hydrolase

WebbIn enzymology, a phloretin hydrolase ( EC 3.7.1.4) is an enzyme that catalyzes the chemical reaction phloretin + H 2 O phloretate + phloroglucinol Thus, the two substrates of this … Webbphloretin hydrolase Alternative Name(s) C-acylphenol hydrolase: Reaction catalysed; H2O + phloretin => 1,3,5-trihydroxybenzene + H(+) + phloretate: Comment(s) Also hydrolyzes other C-acylated phenols related to phloretin. Isolated from the fungus Aspergillus niger and the bacteria Pantoea agglomerans and Eubacterium ramulus.

UniProt

Webb19 feb. 2024 · Two members of the PhlG family have been separately identified as 2,4-diacetylphloroglucinol (2,4-DAPG) hydrolase and phloretin hydrolase; however, the … WebbPhloretin hydrolase SpringerLink Enzyme Handbook 4 pp 1131–1134 Cite as Phloretin hydrolase Dietmar Schomburg & Margit Salzmann Chapter 16 Accesses Keywords Molecular Weight Crystall Ization Bond Cleavage Aspergillus Niger Catalysed Reaction These keywords were added by machine and not by the authors. clothing baby https://telefoniastar.com

Discovery and structural analysis of a phloretin hydrolase …

WebbAbstract. A metagenome expression library of bulk DNA extracted from the rumen content of a dairy cow was established in a phage lambda vector and activity-based screening employed to explore the functional diversity of the microbial flora. Twenty-two clones specifying distinct hydrolytic activities (12 esterases, nine endo-beta-1,4-glucanases ... WebbPhlorizin is a glucoside of phloretin, a dihydrochalcone. A white solid, samples often appear yellow owing to impurities. It is of sweet taste and contains four molecules of water in the crystal. Above 200 °C, it decomposes to give rufin. It is poorly soluble in ether and cold water, but soluble in ethanol and hot water. byrne\u0027s pub brunswick me

Information on EC 3.7.1.4 - phloretin hydrolase

Category:Lactase-phlorizin hydrolase - Lactase-phlorizin hydrolase

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Phloretin hydrolase

Lactase-Phlorizin Hydrolase - MeSH - NCBI

Webb19 feb. 2024 · Two members of the PhlG family have been separately identified as 2,4-diacetylphloroglucinol (2,4-DAPG) hydrolase and phloretin hydrolase; however, the extent of functional divergence and catalytic substrates for … WebbEC Tree. 3 Hydrolases. 3.7 Acting on carbon-carbon bonds. 3.7.1 In ketonic substances. 3.7.1.4 phloretin hydrolase. IUBMB Comments. Also hydrolyses other C-acylated phenols related to phloretin. Isolated from the fungus Aspergillus niger and the bacteria Pantoea agglomerans and Eubacterium ramulus. Specify your search results.

Phloretin hydrolase

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WebbIn enzymology, a phloretin hydrolase(EC3.7.1.4) is an enzymethat catalyzesthe chemical reaction The Enzyme Commission numberis a numerical classification scheme for … Webb2,4-DAPG; Friedel–Crafts hydrolase; MAPG; PhlG; phloretin hydrolase Correspondence Y.-X. He, MOE Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou 730000, China Tel: +86 0932 8912563 E-mail: [email protected] Jian-Ting Han and Si-Ping Zhang contributed equally to this work

Webb16 okt. 2024 · It possesses a phloretin-hydrolase able to break the phloretine C-C bond . Another anaerobic bacterium isolated from human feces, Clostridium orbiscindens, was found to degrade apigenin to 3-(4-hydroxyphenyl)propionic acid with phloretin and naringenin as the two intermediates . Webb1 apr. 2024 · Two members of the PhlG family have been separately identified as 2,4-diacetylphloroglucinol (2,4-DAPG) hydrolase and phloretin hydrolase; however, the extent of functional divergence and catalytic substrates for most members of this family is still unknown ... Macromolecules Find similar proteins by: (by identity cutoff) 3D Structure

Webb14 nov. 2013 · Phloretin hydrolase from Eubacterium ramulus (Phy) catalyzes the hydrolysis of the dihydrochalcone phloretin to phloroglucinol and phloretic acid, performi … WebbAlso hydrolyses other C-acylated phenols related to phloretin. Isolated from the fungus Aspergillus niger and the bacteria Pantoea agglomerans and Eubacterium ramulus. History. EC 3.7.1.4 created 1972, modified 2024. Pathway. ec00946. Degradation of flavonoids. ec01100. Metabolic pathways.

Webb1 okt. 2004 · The phloretin hydrolase was heterologously expressed in Escherichia coli and purified. The molecular mass of the native enzyme was approximately 55 kDa as …

Webb1 maj 2024 · Phloretin, a plant-derived dihydrochalcone compound, was reported to have the activities in regulating metabolism homeostasis and anti-inflammation. However, its effects and the mechanism on early stage endothelial injury caused by … byrne\u0027s towing serviceWebbAn inducible hydrolase from Aspergillus niger, acting on carbon-carbon bonds, for phlorrhizin and other C-acylated phenols. Biochem. J. 116 (1970) 889–897. [PMID: 5441377] 3. Schoefer, L., Braune, A. and Blaut, M. Cloning and expression of a phloretin hydrolase gene from Eubacterium ramulus and characterization of the recombinant … byrne used carsWebbphloretin hydrolase1-[2,4,6-tris(oxidanyl)phenyl]ethanone. NCBI. National Center for Biotechnology Information. Search. 5XEY: Discovery and structural analysis of a phloretin hydrolase from the opportunistic pathogen Mycobacterium abscessus. PDB ID: 5XEY Download: MMDB ID: 161436: PDB Deposition Date: 2024/4/6: Updated in MMDB: 2024/05: byrne\\u0027s pub columbus ohioWebbInhibitor in Enzyme-catalyzed Reactions (18 results) compound shows little anti-Staphylococcus aureus activity, but significantly inhibit SrtB activity in vitro. Phloretin reduces human alveolar epithelial cell damage caused by Staphylococcus aureus. Phloretin directly localizes in the active pocket of SrtB and blocks substrate binding. byrne\u0027s pub grandviewWebb19 feb. 2024 · The phloretin hydrolase ErPhlG was the first characterized PhlG homologous protein through gene library based biochemical screening . Based on this … byrne\u0027s pub columbus ohioWebbLactase-Phlorizin Hydrolase. A multifunctional protein that contains two enzyme domains. The first domain (EC 3.2.1.62) hydrolyzes glycosyl-N-acylsphingosine to a sugar and N … byrne\\u0027s towing serviceWebb1 mars 2014 · Phloretin hydrolase catalyzes the hydrolytic C-C cleavage of phloretin to phloroglucinol and 3-(4-hydroxyphenyl)propionic acid during flavonoid degradation in Eubacterium ramulus. clothing baby girl