WebApr 3, 2024 · The transport of multivesicular bodies (MVBs) after overexpression of HOTAIR was detected by transmission electron microscopy and confocal microscopy analysis of cluster determinant 63 (CD63) with synaptosome associated protein 23 (SNAP23). The mechanism of HOTAIR’s regulation of Ras-related protein Rab-35 (RAB35), vesicle … WebHOTAIR was the first lncRNA to be identified for its role in metastasis. Overexpression of HOTAIR is associated with metastasis in multiple cancers, including breast, pancreatic, …
HOTAIR - an overview ScienceDirect Topics
WebNon-coding RNAs are emergent elements from the genome, which do not encode for proteins but have relevant cellular functions impacting almost all the physiological processes occurring in eukaryotic cells. In particular, microRNAs and long non-coding RNAs (lncRNAs) are a new class of small RNAs transcribed from the genome, which modulate … WebApr 12, 2024 · Carolina BalloonFest is the second-oldest hot air balloon festival in the world and been running for nearly 50 years. The Statesville -based festival brings in close to … small standalone cabinet for bathroom
Inducible lncRNA transgenic mice reveal continual role of HOTAIR …
WebNext, HOTAIR overexpression was transfected into H9c2 cells and exposed to H/R. qRT-PCR results showed that HOTAIR overexpression attenuated the up-regulation of miR-17-5p expression induced by H/R . Western blot verified that HOTAIR overexpression partially reversed H/R-induced down-regulation of p-STAT3 expressions ( Figure 4B and C ). WebFeb 7, 2024 · Downregulation of HOTAIR was detected in osteosarcoma, which predicted poor prognosis of patients with osteosarcoma. Moreover, cell migration, invasion, and proliferation were suppressed by HOTAIR overexpression in osteosarcoma. Furthermore, LPR5 was a direct target of HOTAIR, which was upregulated in osteosarcoma. WebApr 15, 2010 · Conversely, overexpression of EZH2 in H16N2 breast cells is known to promote matrix invasion 12, but concomitant depletion of endogenous HOTAIR in large … highway alliance